2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. ATP Synthase

ATP Synthase

ATP Synthase

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ATPases are a class of enzymes that catalyze the decompositionof ATP into ADP and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. Some such enzymes are integral membrane proteins and move solutes across the membrane, typically against their concentration gradient. These are called transmembrane ATPases. Transmembrane ATPases import many of the metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes. Such as the sodium-potassium exchanger (or Na+/K+ ATPase) and the hydrogen potassium ATPase (H+/K+ ATPase or gastric proton pump) that acidifies the contents of the stomach.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-150983A
    ATP synthase inhibitor 2 TFA
    		Inhibitor 99.97%
    ATP synthase inhibitor 2 (Compound 22) TFA is a Pseudomonas aeruginosa (PA) ATP synthase inhibitor (IC50=10 μg/mL). ATP synthase inhibitor 2 TFA can inhibit Pseudomonas aeruginosa (PA) ATP synthesis activity completely at 128 μg/mL.
    ATP synthase inhibitor 2 TFA
  • HY-157046
    ATP Synthesis-IN-2
    		Inhibitor
    ATP Synthesis-IN-2 (Compound 5) is an antibacterial compound. ATP Synthesis-IN-2 is a potent ATP synthesis activity inhibitor with IC50 against Pseudomonas aeruginosa (PA) Value of 0.7 μg/mL.
    ATP Synthesis-IN-2
  • HY-157045
    ATP Synthesis-IN-1
    		Inhibitor
    ATP Synthesis-IN-1 (Compound 4), quinoline derivative, is a potent inhibitor of PA ATP synthesis activity. ATP Synthesis-IN-1 has PA ATP synthesis inhibition with IC50 value of 11.1μg/mL. ATP Synthesis-IN-1 also has antibacterial activity. ATP Synthesis-IN-1 can be used for the research of drug-resistant PA infection.
    ATP Synthesis-IN-1
  • HY-149736
    ATP Synthesis-IN-3
    		Activator
    ATP Synthesis-IN-3 (compound 31) is an ATP hydrolysis inhibitor with protective effects during myocardial ischemia. ATP Synthesis-IN-3 can increase the ATP content of ischemic cardiomyocytes, increase the phosphorylation of PKA and phospholamban, and inhibit ischemia-induced apoptosis.
    ATP Synthesis-IN-3
  • HY-N12486
    Isofalcarintriol
    		Inhibitor
    Isofalcarintriol is a NRF2 activator and selective inhibitor of the mitochondrial ATP synthase. Isofalcarintriol can be used for aging study.
    Isofalcarintriol
  • HY-155754
    3′-Acetate-ATP
    		Inhibitor
    3’-Acetate-ATP, an ATP analogue, is ATP acetylation product with an maxima uv absorption at 259 nm in water at neutral pH. 3’-Acetate-ATP exerts a blocking effect on nucleic acid polymerization.
    3′-Acetate-ATP
Cat. No. Product Name / Synonyms Application Reactivity